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  • Are You Food Intolerant? - by Dr Gill Hart

    Paula Radcliffe feeds back to YorkTest about the impact of targeted dietary change on her performance


    Paula Radcliffe doesn’t require any introduction; double gold medalist at the World Cross-Country Championships; British 3000m and 5000m record holder; European 10,000m record holder; triple gold medalist at the London marathon; World Record holder for the road-10km and Half Marathon and most notably, the World Record holder for the Marathon. However, success for Paula hasn’t always been easy, and, like the estimated one quarter to one half of elite athletes that are hampered by gastrointestinal symptoms , Paula has suffered too.

    At the Athens Olympics in 2004, which Paula described to the BBC as the worst moment of her career, she was unable to finish the race. She said “I felt there was nothing in my legs, you go through bad stages in a marathon, but never as bad as that. I've never before not been able to finish and I'm desperately trying to find a reason for what happened”.

    In most cases the overall cause of exercise related gut problems isn’t clear and many factors have been implicated including stress, medications, dehydration, infections and of course diet. After a colonoscopy and coeliac test gave Paula the all clear, YorkTest Laboratories (yorktest.com; Tel: 0800 074 6185) analysed Paula’s blood sample; just a couple of drops from a finger-prick are all that is needed. The test identified sensitivities to chicken, egg whites, wheat, gluten, soya, oats and tomatoes.

    Paula told us that “After I cut these foods out of my diet, I was able to run without doubling up in pain. I have a lot more energy and I am back to my normal self. It truly made such a difference to my life and I would recommend it to anyone else suffering from symptoms like these.”

    Our digestive system contains more immune cells and produces more antibodies than any other organ in the body. Our gut lining acts as a second “skin”; a highly selective barrier that is in place to protect our internal environment; protecting us from harmful toxins, bacteria and incompletely digested foods, yet making sure that essential nutrients and digested foods are freely allowed into the bloodstream. This balance between an efficient passage of nutrients and the restriction of the entry of larger molecules, such as larger proteins, is absolutely critical to energy balance and sports performance. If the barrier fails for any reason, this can lead to an increase in the passage of allergens and larger food particles that have been linked with inflammation and food intolerance symptoms. The inflammation in turn can cause further damage and a vicious circle of increased gut permeability.

    How then to break that vicious circle? You give yourself an easy route map by identifying the foods from your diet that your body is reacting to, and then removing them from your diet. In order to optimise the absorption of essential nutrients our gut needs all the help and support that it can get. Healing the damage takes time, but can be achieved and trigger foods can often be reintroduced gradually after a few months.

    As soon as Paula started to cut her trigger foods out of her diet she noticed a difference and she was able to function normally again. Paula was able to continue training and her performance improved, going on to achieve the world record! “I was back to my normal training regime in no time. YorkTest made such a difference to my life because the test identified foods that my body had a bad reaction to and I was able to stop the symptoms before they reached the extreme level I experienced during the Athens Olympics.

    The YorkTest “First Step” food intolerance test kit is available at myprotein.com for £9.99


    Dr Gill Hart is a PhD Biochemist with over twenty years experience in the development and clinical evaluation of diagnostic tests. Gill joined the YorkTest team in 2005, and has applied her scientific and regulatory knowledge to all YorkTest services; including putting in measures of ‘self-regulation’ in the under-regulated ‘diagnostic testing services’ industry. Gill regularly gives talks and lectures at Universities and Colleges. She also provides guidance for those choosing diagnostic tests with her ‘What makes a good diagnostic test’ checklist, and has written many articles in scientific journals and consumer magazines.


    Discuss on the MP Forum.
    Comments 17 Comments
    1. Odevans's Avatar
      Quite tempted to have have a food intolerance test.

      How much does the 'FoodScan 113', actually cost?
    1. MJ.23's Avatar
      The tester kit costs £9.99. This will tell you if you have a intolerance or not. The actual tests costs a whopping £250.

      The big issue I have with this testing kit is that it tests people against such a wide array of food items that the testing kit will read positive in 99% of cases.

      Along with this is the still controversial scientific background of food intolerance testing. Two tests from seperate labs will most likely not agree. If I visited all testing labs and aquired results from each of them; combined they would indicate I have an intolerance to everything on the planet.

      The medical community are still finding it difficult to even acknowledge food intolerances; hence why this field is still in its infancy. Some doctors are so arrogant on this topic they completely refuse to believe that food can have a negative effect on someones' health. This is another big failing of our health industry.

      Imo; trial and error (and time) are still the best options.
    1. MiniHulk's Avatar
      I am intolerant to EVERY food right now, the healing phase is going to be arduous lol.

      I would love to watch the test explode after I used it though, haha.
    1. Odevans's Avatar
      £250!

      For that, I could purchase every food that I'd be tasted against, and find out for myself, about 20 times over! Yeah, to hell with that!

      MH, you remind me of a friend of mine. She has an intolerance to pretty much everything! Not fair at all. Heal up quickly, and properly, mate.
    1. grhart's Avatar
      Quote Quote
      Originally Posted by MJ.23 View Post
      The tester kit costs £9.99. This will tell you if you have a intolerance or not. The actual tests costs a whopping £250.

      The big issue I have with this testing kit is that it tests people against such a wide array of food items that the testing kit will read positive in 99% of cases.

      Along with this is the still controversial scientific background of food intolerance testing. Two tests from seperate labs will most likely not agree. If I visited all testing labs and aquired results from each of them; combined they would indicate I have an intolerance to everything on the planet.

      The medical community are still finding it difficult to even acknowledge food intolerances; hence why this field is still in its infancy. Some doctors are so arrogant on this topic they completely refuse to believe that food can have a negative effect on someones' health. This is another big failing of our health industry.

      Imo; trial and error (and time) are still the best options.

      It is true that two tests from separate labs will most likely not agree but the YorkTest programme is the only one of its kind that has scientific data to back it up, the only one of its kind recommended by the leading medical charity Allergy UK, doesn't give 99% positive results (hence the use of the yes / no First Step test), and also offers Nutritional Therapist consulations as part of the service (hence the cost!). Certainly agree with comments about the food intolerance field being in its infancy; with Allergy UK statistics stating food intolerance rates at 45% of the population this is something that can't be ignored! Our experience is that many people suffer from food intolerance symptoms such as gut problems, skin problems, headaches and migraine for many years without help before coming to YorkTest and the programmes that we offer have benefitted many thousands over the nearly 30 years we have been around.

      Hope this helps.
      Dr Gill Hart
    1. MiniHulk's Avatar
      Quote Quote
      Originally Posted by grhart View Post
      It is true that two tests from separate labs will most likely not agree but the YorkTest programme is the only one of its kind that has scientific data to back it up, the only one of its kind recommended by the leading medical charity Allergy UK, doesn't give 99% positive results (hence the use of the yes / no First Step test), and also offers Nutritional Therapist consulations as part of the service (hence the cost!). Certainly agree with comments about the food intolerance field being in its infancy; with Allergy UK statistics stating food intolerance rates at 45% of the population this is something that can't be ignored! Our experience is that many people suffer from food intolerance symptoms such as gut problems, skin problems, headaches and migraine for many years without help before coming to YorkTest and the programmes that we offer have benefitted many thousands over the nearly 30 years we have been around.

      Hope this helps.
      Dr Gill Hart
      Does the nutritional therapist really make it worth £250 though? Sorry to sound like an a** but you need to push harder than that for some people to believe it is worth undertaking. The other thing is; if you tell someone that they have an intolerance then they will eat that food even more because it is a taboo lol. I am not allowed to eat sugar, which makes me want it even more :|
    1. purplecat84's Avatar
      Quote Quote
      Originally Posted by Odevans View Post
      Quite tempted to have have a food intolerance test.

      How much does the 'FoodScan 113', actually cost?
      EDIT- MP took ages to post my reply that it's totally out of date!
    1. grhart's Avatar
      Quote Quote
      Originally Posted by MiniHulk View Post
      Does the nutritional therapist really make it worth £250 though? Sorry to sound like an a** but you need to push harder than that for some people to believe it is worth undertaking. The other thing is; if you tell someone that they have an intolerance then they will eat that food even more because it is a taboo lol. I am not allowed to eat sugar, which makes me want it even more :|
      It's true that it's the foods that you are intolerant to that you crave!! I guess it depends how much you want to feel better / improve as to whether you take the foods out of your diet. It's not always easy to change diet, hence the 2 x half hour consultations with a BANT* registered Nutritional Therapist. The blood test also picks up reactions to 113 different foods and the results include a guidebook and food diary. Hope this helps. Dr Gill Hart

      *British Association of Nutritional Therapists
    1. MiniHulk's Avatar
      Thanks for taking the time to post on here, it will definitely help people decide whether to have it done. I agree that if someone is suffering enough then they will do everything they can.
    1. Ben Coomber's Avatar
      Interesting to note that the foods that came up were the foods that likely formed the basis of Paula's diet before she was tested "chicken, egg whites, wheat, gluten, soya, oats and tomatoes" - showing that over comsumption of food sources will develop issues. Identifying intolerances are so essential to optimal health and performance, for everyone!
    1. Bebop1980's Avatar
      Say £199 quid on the product page.
    1. hailtotheking's Avatar
      I would say an MRT test is more useful than the Foodscan test. The MRT test can pick up IgG AND IgM antibody reactions to food as well as other types of Hypersensitivity reactions, wheras the Foodscan test only picks up IgG reactions.

      Although its from the head of Signet MRT, this is an interesting snippet discussing MRT and IgG testing, and the differences:

      Quote Quote
      The Mediator Release Test (MRT)

      Q. Is MRT accurate?
      A. A blinded peer reviewed scientific study showed MRT to have the highest level of accuracy of
      any food sensitivity blood test (94.5% sensitivity and 91.8% specificity).

      Q. What’s the difference between MRT and other tests for food sensitivities?
      A. There are a few different tests available that are intended to identify sensitive foods. They are
      IgG (ELISA or RAST), ALCAT, and LRA by Elisa-Act (not to be confused with ELISA IgG). Without
      understanding some basics, it’s impossible to understand how one is superior to the others and how they compare.

      The Basics:
      Food sensitivities make a person feel sick because the immune system reacts to foods and causes the release of chemicals called mediators (such as histamine, prostaglandins, cytokines, etc.) from white blood cells. It’s the mediators that cause the inflammation, pain, and other symptoms associated
      with food sensitivities. In fact, food sensitivity is a very complex reaction by our immune system. There are many different cells that have different profiles of mediators, many mechanisms that cause mediators to be released, and of course, many different mediators. The thing that makes food sensitivities complicated is that there are various ways the immune system can respond in hypersensitivity. Because there are different ways the immune system can respond, there are different approaches researchers have tried to identify reactive foods and chemicals.

      ELISA IgG: This test quantifies how much IgG you are producing to a specific food, with the assumption that high levels of IgG are only a bad thing. There is a specific type of immune reaction called Type 3 Hypersensitivity that can involve IgG or another antibody called IgM. When IgG is involved in triggering mediator release, this testing will be very helpful. Unfortunately, there are three very serious limitations of IgG testing:

      1. High levels of IgG can be either good (suppressing of an immune response) or bad (causing an immune response). But you cannot tell which is good IgG or which is bad IgG through this testing. Having a high level may actually be good -- not bad.

      2. IgG only plays a minor role in IBS, migraine, and fibromyalgia. Instead, research shows that Type 4 Hypersensitivity is the primary type of reaction. Type 4 Hypersensitivity doesn’t involve IgG or any other antibodies.
      3. IgG testing cannot identify reactions to chemicals like food additives. It’s clearly documented that food chemicals play a very important role in provoking symptoms in many conditions. If you cannot identify these reactions, you could very well be missing very important information that can impact your health.

      How MRT Compares to IgG: There are a number of advantages of MRT over any form of IgG testing.
      MRT is an endpoint test, meaning that all the immune based adverse reactions end up causing mediator release. So MRT tests for the release of mediators without caring about the mechanism. In fact, by testing for mediators which are the endpoint of immune reactions, MRT is able to take into account the actions of all mechanisms, whether they are antibodies or other, because all of them ultimately cause white blood cells to release mediators. MRT is able to account for a much wider array of reactions than the relatively simple IgG testing. In addition, MRT is able to identify reactions to chemicals. Overall, MRT is more accurate and useful clinically.

      The ALCAT Test: The ALCAT Test was invented and patented by the same person who invented and patented MRT, Dr. Mark Pasula. The two technologies are similar, yet separately patented, which means there is a unique difference. The main difference between the two tests is in terms of accuracy and reliability. Side by side studies have shown MRT to be more accurate (higher sensitivity and specificity) and to have higher split sample reproducibility than ALCAT. It is a good, but older method that has been replaced by the newer, better technology used in MRT.

      LRA by ELISA-Act: This test is somewhat of a mystery as to what it actually measures and how that correlates with mediator release and with an involvement in IBS, migraine, fibromyalgia, or other foodsensitivity-related conditions. The company that invented it makes claims about its accuracy, reproducibility, and validity, but in fact there are no actual third party studies that confirm any of their claims. Nor have their own studies related to the same been published. In other words, there are no published studies that support their claims. In addition, the actual methodology is not described or validated in any peer reviewed publications, yet they claim that it is. Therefore it’s not possible to assess and compare its strengths and weaknesses to MRT.

      MRT: The main difference between MRT and ELISA-Act is that of scientific validation. There are studies published on MRT that clearly show the methodology, accuracy, ability to discriminate between healthy and sick populations, etc. They clearly tie the relationship of what MRT is measuring to the physiological basis of adverse food reactions in IBS, migraine, fibromyalgia, and other foodsensitivity-related conditions.

      Q. How does MRT work?
      A. MRT is an indirect method of accurately measuring mediator release. MRT does this by measuring changes in the liquids to solids ratio of your blood after your blood has been exposed and incubated with the test substance. It accounts for all reactions by your immune cells. This is done as an indicator that your immune cells have released chemical mediators such as histamines and others. Significant reactions are broken into either Reactive (Red), or Moderately Reactive (Yellow) categories and insignificant reactions (Green) are placed in the Low-Reactive category. All measurements are made using the most accurate method of measurement (Ribbon technology) currently available.
    1. hailtotheking's Avatar
      Quote Quote
      Originally Posted by Ben Coomber View Post
      Interesting to note that the foods that came up were the foods that likely formed the basis of Paula's diet before she was tested "chicken, egg whites, wheat, gluten, soya, oats and tomatoes" - showing that over comsumption of food sources will develop issues. Identifying intolerances are so essential to optimal health and performance, for everyone!
      An iGg response to a food you consume a lot does not necessarily indicate problems. See my previous post.
    1. MartinM's Avatar
      Quote Quote
      Originally Posted by hailtotheking View Post
      An iGg response to a food you consume a lot does not necessarily indicate problems. See my previous post.
      Agreed.

      IgG is a relatively useless measure of food intolerance. Trial and Error is as, if not more, effective and is a lot cheaper too.
    1. Ben Coomber's Avatar
      Hail to the king, I was the 1st person to post but somehow the comment took ages to appear, I agree and personally think trial and error through elimination is the way to go, and its the best educational process for the person doing it, either way I like the MRT!
    1. ReeceMander's Avatar
      Quote Quote
      Originally Posted by MartinM View Post
      Agreed.

      IgG is a relatively useless measure of food intolerance. Trial and Error is as, if not more, effective and is a lot cheaper too.
      I disagree. Trial and error is not more effective as some responses are delayed and can show up after two weeks. LEAP/MRT testing is highly effective and well worth the money in my opinion. Removing the intolerant foods will allow you to concentrate on healing the gut
    1. MartinM's Avatar
      Quote Quote
      Originally Posted by ReeceMander View Post
      I disagree. Trial and error is not more effective as some responses are delayed and can show up after two weeks. LEAP/MRT testing is highly effective and well worth the money in my opinion. Removing the intolerant foods will allow you to concentrate on healing the gut
      I personally conducted an industry funded research study on Elisa IgG testing.... based on this results of this it is my opinion that Trial and Error/Food Elimination is more useful than IgG testing.. I think proponents of MRT tend to agree with this... but I'm no expert on MRT.

      Some responses can show up after two weeks? Can you expand a little more on that?
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