http://www.caloriesperhour.com/tutorial_thermic.phpQuote
The expression "thermic effect of food" is used to describe the energy expended by our bodies in order to consume (bite, chew and swallow) and process (digest, transport, metabolize and store) food. We "expend energy" by burning calories.
Processing protein requires the greatest expenditure of energy, with estimates ranging as high as 30%. Dietary fat, on the other hand, is so easily processed and turned into body fat that there is little thermic effect, perhaps only 2 or 3%. The amount of energy required to process carbohydrates falls between that of protein and fat.
As you can see when it comes to extracting energy from macronutrients, fats are the most efficient while protein is the least efficient with carbs falling somewhere between the two.
So, if as much as 30% of the energy obtained from protein would need to be used up in order to extract it, then you would need to expend 1.2 kcals for every 2.8 kcals of usable energy derived from each gram of protein. If you consume 25g of protein (100 kcals) you use up 33 kcals of that leaving 67 kcals (which is why protein foods are slimming!). However, if the majority of the calories going into your body are provided by proteins then you are not gaining the full measure of daily calories you may require for optimum health. If you require 3000 kcals per day and 40% was from protein and the remaining 60% from fats, it would break down like this:
3000 x 0.4 = 1200 less 30% for TEF = 840
3000 x 0.6 = 1800 less 3% for TEF = 1746
Total usable calories = 2586 (-414) 13.8% reduction
If you reverse the macro percentages so that protein is 60% of total calories and fat is only 40% you get this:
3000 x 0.6 = 1800 less 30% TEF = 1260
3000 x 0.4 = 1200 less 3% TEF = 1164
Total usable calories = 2424 (-576) 19.2% reduction
Each time you ratchet protein up and fats down you effectively get fewer usable calories from the same intake - good for slimming but bad if you need to survive in a harsh environment where food is in limited supply and you have to work physically hard to get it! In other words you would have to effectively eat more total calories in order to supply the body with its daily calorie requirement if it was made up mostly of protein and very little fat (and/or carbs). Not ideal if you are subsisting.
That is the essence of 'rabbit starvation' - too few calories gained by eating a lean meat diet.


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